Recombinant Canine Interleukin-8CXCL8

Recombinant Canine Interleukin-8/CXCL8

Author: ApexBio

spu:

P1367

purity:

> 95 % by SDS-PAGE and HPLC analyses.
Endotoxin: Less than 1 EU/μg of rCaIL-8/CXCL8 as determined by LAL method.

M.Wt:

Approximately 9.1 kDa, a single non-glycosylated polypeptide chain containing 79 amino acids.

DeliveryTime:

Ship with 5-10 days

jib-04 Purity

ShippingType:

Blue ice

description:

Interleukin-8 (IL-8) is encoded by the IL8 gene andproduced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles. There are many receptors capable to bind IL-8, the most affinity to IL-8 are receptors CXCR1, and CXCR2. As a member of the CXC chemokine family, function of IL-8 is the induction of chemotaxis in its target cells, like neutrophil granulocytes, basophils, and T-cells. . IL-8 is often associated with inflammation and has been cited as a proinflammatory mediator in gingivitis and psoriasis.

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